Friday, October 11, 2019

Why do perfect IVF cycles fail?

Often an IVF cycle goes perfectly , and the doctor is happy with the medical process. He has transferred a top quality blastocyst; the transfer was smooth; and the endometrium was 8 mm and trilaminar.
However, even though everything seems to be perfect, the IVF cycle may still fail.
Patients then feel  cheated and upset ! After all, if the cycle was perfect and the doctor was so happy and hopeful, then why didn't it work?
What they forget is that when we call a cycle perfect, we only refer to the medical tangibles  which we can measure. Our technology is still not good enough to allow us to assess all the hundreds of variables which influence implantation.
Thus, we look at the morphology of an embryo and grade it, but we can't check its genetics. Similarly, while we can see that the endometrium is thick and trilaminar on an ultrasound scan, this doesn't necessarily mean that it's receptive, and we don't have the tests to be able to assess this.
It's because our technology is limited that a perfect IVF cycle doesn't always end in a pregnancy.
This is something we need to learn to live with, because reproductive science is still not perfect.

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