Thursday, March 22, 2012

Symptoms after embryo transfer

As any IVF patient will attest, the 2 week wait after the embryo transfer are the longest 15 days in your life. All the action and the excitement of taking injections , going for scans , monitoring your blood test results and admiring your embryos is now over. Your doctor has put your embryos back into your uterus - and now all you can do is wait for the final outcome , in order to find out whether the embryos have implanted are not. Not only is the fact that the outcome of the treatment completely out of your hands extremely frustrating, what makes it even worse is that there is no way to of finding out what is happening to your precious embryos inside your body.

Your doctor is not very helpful either , because he's finished doing whatever he can do . He just tells you to be patient and wait till you get the HCG result . It's easy for him to say this , because he has other patients to treat - but how do you deal with the uncertainty , the impatience and the anxiety of those 15 days - where every minute seems to last an hour.

Your mind plays all kinds of games with you ! Do my breasts feel more tender than usual ? I am feeling nauseous – is this early morning sickness and does this mean that my embryos have implanted ? Should I panic because I am not feeling anything at all ? Does this mean that my embryos have died and that they cycle has failed ? Was that blood in my vaginal discharge ? Does that mean my embryos are falling out ? Are my symptoms because of PMS or are they a side effect of the medications I'm taking ?

Your mind is full of doubts and questions and there is really no one who can provide the answers. There’s little point in asking your doctor , because most the time all he can say is – We’ll have to wait for the blood test results to find out what’s happening. You can't keep on bothering your husband , which is why you spend hours on the net , googling your symptoms . You try to make sense of them by asking other more experienced IVFers on online IVF bulletin boards , so you can compare what’s happening to you with their experiences. These expeditions often leave you even more confused and frustrated, because there’s so much variability , and so many old wive’s tales !

What you need is emotional support to calm your anxious mind , but while your head understands this, it's very hard for your heart to come to terms with the fact that these 15 days will also pass. You try to do everything possible to maximize your chances of success. Your friend’s mother-in-law suggested that you should be resting in bed , so you spend all day , lying down. You read somewhere that eating pomegranates is good for your fertility , so you drink a bottle of pomegranate juice daily. The nurse at the IVF clinic suggested that you should be eating a lot of pineapples , so you eat a tin-full of slices daily; and your online buddy suggested that royal jelly helps embryos to implant, so you dutifully buy this and consume it religiously.

You try to stop your mind from playing games , by using meditation and other mind-body control techniques, but nothing seems to work . You are dying to find out what's happening inside you , and you start cheating by doing pregnancy tests 4 days after the transfer, even though you know it's too early to really get an answer one way or the other . When you see a second line, you wonder whether it's an optical illusion , or whether you are actually be pregnant.

You just can't understand why your husband is not as obsessed about the result as you are – and because he's busy with his work and you can't keep on bugging him about your feelings and your symptoms every day , you try to bottle them up.

When it's D-day and you go to do your pregnancy test , you are not sure whether you're happy that you are finally going to find out what the results are you . You are so scared , that you find yourself trembling with anxiety. This is not the sort of person you normally are. You are used to being in control of your life and to making decisions for yourself . You find it difficult to understand why you are behaving like a student who's waiting to find out what her exam results are . And then starts the final wait to find out what the results – and every time the telephone rings , you are never sure whether you should pick it up because the nurse may be calling with good news – or not !

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74 comments:

Anonymous said...

Dear Dr,


Beautiful post! How can you put yourself in someone’s shoes? Your blog is a life-saver for me (I really mean it!) I would like to add a few more funny things that we do during 2ww.

As the dooms day (testing day!) approaches there will be more frequent trips to restroom. The frequency can be as high as once in every 15 minutes. The reason is to check for bleeding. Will the ugly AF arrive? Those are the most panicky moments!

We try to feel our skin more often to confirm that our body is warm enough. More warm the body is, the better we feel (hotter the better!). For some reasons, when our skin feels colder we start to panic! And when it becomes warmer again our hope rises again! If someone asks by chance, ‘why is your body too warm?’ we will be super duper happy and ask them again whether what they said a few seconds back is true (just to confirm!)? We never mind the fact that they are looking at us as if we are some stupid, crazy creatures: D

I ask my DH to touch one of the two fingers I show him. He will be safe if he selects the right finger the first time around (you should see my DH’s face at that time, he will be too tensed and at the same time unable to refuse or say anything because of the fear of potential crying spells!). The process will be repeated several times until the result of the touch says that the outcome of ET will be positive :)

When going for bath the water temperature will be checked several times, obsessively. Remember, do not indulge in warm baths which has the potential to raise your body temperature! If you are living in a cold country never take a bath! :D

We look at the pregnancy test kit in all different angles and in all different lighting! (day light (both morning and evening), tube light, under a bulb etc) Even if no one sees a line our powerful eyes will definitely see a faint line. If our DH is unable to see it we go crazy. We never throw away any negative pregnancy test kits. Even if we throw them in dustbin they will be excavated (!) out very soon. We save it carefully and look at it again some seconds later, some minutes later, some hours later (the process continues until a new test is done!). We even break open the pregnancy test kit to take out the strip and see it again under different lightings (better view!)

Anonymous said...

After few IVF cycles we realize that home pregnancy tests are evil and we promise not to use them during 2ww! The reason is- why to spoil the happiness of those 15 days with a stupid pee stick! At least those 15 days we want to stay pregnant (pregnant until proven otherwise!)

We feel very happy when we get up several times in the night to use the toilet. Might be HCG is building up! Progesterone levels are getting stronger!

In short, whatever is uncomfortable for a normal woman is a blessing for us. Bring on more breast tenderness, more bloating, more constipation, and more frequent trips to loo, even OHSS (sign that you may be pregnant!), more nausea, more headaches and more pain! When our body feels normal we become abnormal!

AND when the pregnancy test comes back negative :(, all the excitement dies down in a second. The reality that it is impossible to see our baby in the next 9 months hits us too hard. We feel horribly disappointed when our DH looks worn-out and tired. At least we woman cry and speak out our pains but men never do! (what will be going on in their mind?!). We take a secret resolution within ourselves that we will never ever go through this IVF hell again!

Surprisingly, few weeks later the thought of a new IVF cycle starts to bud out and grow. The desire to create our baby, the burning desire to perpetuate our genes rejuvenates our entire system. Our mind and body forgets the old disappointment and starts to get ready for the next cycle. Hope blooms again and we get ready with lots of enthusiasm for the next roller-coaster ride. After all, roller-coaster rides are fun, isn’t it?

“Never let go of hope. One day you will see that it all has finally come together. What you have always wished for has finally come to be. You will look back and laugh at what has passed and you will ask yourself... 'How did I get through all of that? ”
- author unknown

Dr Aniruddha Malpani, MD said...

As long as you keep your sense of humour, you'll be fine !

Dr Aniruddha Malpani, MD
Malpani Infertility Clinic, Jamuna Sagar, SBS Road, Colaba
Bombay 400 005. India
Tel: 91-22-22151065, 22151066, 2218 3270, 65527073

Helping you to build your family !

My Facebook page is at www.facebook.com/Dr.Malpani

You can follow me on twitter at http://twitter.com/#!/drmalpani

Watch our infertility cartoon film at http://www.ivfindia.com

Read our book, How to Have a Baby - A Guide for the Infertile Couple,
online at www.DrMalpani.com !

Read my blog about improving the doctor-patient
relationship at http://blog.drmalpani.com

Anonymous said...

Thank you very much Dr! :) Have a weekend filled with lots of laughter and happiness!

Anonymous said...

After 2 eggs being transfer an one works do you get s discharge on the second egg

Dr Aniruddha Malpani, MD said...

No. If 2 embryos are transferred, and if only 1 implants, the other embryo dies and is reabsorbed silently by the body. There are no symptoms or signs, because it's only a microscopic ball of cells.

Anonymous said...

Hi.I had my 3day embryos transfer 8 days ago.from 3 days I got severe period pain during the night most.today the 8th day, after wake up and shower I don't feel anything, just bloating after drinking liquids(water,tea, juice).this mean my embryos not implanted ?

Dr Aniruddha Malpani, MD said...

No, please do not jump to conclusions. It's impossible to predict from your symptoms whether or not your embryos have implanted.

Best of luck !

Anonymous said...

Hye Dr.. Today is the 3rd day past my 5 days transfer and I really don't have any symptoms at all like creamping,headache or nausea. Is that a bad sign,Dr..??

Thanks Dr.

Anonymous said...

Hi doctor! Am 5 days post embryo transfer( frozen icsi) as part of my natural cycle. Today all day I have be experiencing a menstrual like cramps with tingling. I vowed not to do a home pregnancy test till the day of my blood which is this wednesday.but I eventually tested tonight and saw a very very faint second line. Am already upset and hyped up thinking my test will come back negative. Could be really pregnant? And why are they testing me 7 days post tranfer instead of the the two weeks?

Dr Aniruddha Malpani, MD said...

A faint second line is a good sign. If you test so early, the line is bound to be faint !

You can try repeating the test after 2 days. If the line becomes darker, this is a good sign :)

Best of luck !

Anonymous said...

Hi doctor,i m on 5th day of my ET and from today i m getting period like pain and some time ovary side pain too. i m very much tensed is it negative sign?coz i m not getting any cramps or nausea...only lower back pain and nipples pain but these symptoms were also last time and i got failed IVF that time.
actually this time after Transfer nurse said to me to empty my bladder right after the process and i stood up right after my ET..

swasti said...

Dear Dr Malpani,

Thank you for this site - you're a blessing.

I had a 5 day transfer of 2 excellent blasocysts + 2 good embroys.
Today is 5 days post transfer, however 2 days ago I started with menstrual cramps and some bleeding which was dark brown in colour. Today I have a full on heavy period with red blood and cloths.
Does this mean the implantation has not worked? Could I still be pregnant?

Swasthika age 37

Dr Aniruddha Malpani, MD said...

Dear Swasthika,

Heavy bleeding is not a good sign, sorry. It suggests the cycle has failed :(

Can you send me more details about your IVF cycle ? What were the meds which were used for
superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood ? What was the endometrial thickness ?
How many embryos were transferred ?
What was the embryo quality ? DO YOU HAVE PHOTOS OF YOUR EMBRYOS ? You can see what embryos should look like at http://www.drmalpani.com/embryos.htm
Can you please send me the printed treatment summary from your IVF clinic ?

Priyanka Sharma said...

Hello Mr Malpani,

I had my ET (5 days blastocyst / 4BC grade) two days before . And it was very very painful . I was actually sweating due to pain during ET process. Is it common? I had very severe back pain . But now I have mild cramps sometimes . No implanatation bleeding yet and no other symptoms. I am on estrogen and progesterone medicine.
Is it a bad sign?

Priyanka

Dr Aniruddha Malpani, MD said...

Dear Priyanka,

Embryo transfers are usually easy and painless. Did you doctor need to use a vulsellum during the transfer ?

Anonymous said...

Hi Dr. Malpani,

Reading your post just brought tears to my eyes. I had 2 5day blastocyst transferred 3days ago and the wait is killing me. May I please ask a question?
My progesterone shots where causing bloating and really sore breast and then last night I had really bad chills. When I woke up this morning my breast are no longer sore and my bloating is disappating.
Should I take this as a possible sign that my embryos did not hatch and implant?
Thank you in advance!

Dr Aniruddha Malpani, MD said...

No, please don't start over-interpreting these symptoms. There's so much overlap between the symptoms of pregnancy and PMS
( premenstrual syndrome) that it's impossible to find out reliably if you are pregnant or not , until you do your HCG blood test.

The progesterone shots are cruel and unkind ! Please ask your doctor to give you the progesterone vaginally - this is much more effective than the painful oily injections !

Priyanka Sharma said...

Hello Dr,

I had my ET on 13 April 2013 and on 19 April my blood report showed 5.6 HCG units. my ET was a frozen 5days blastocyst.Is it a good sign. Does it mean that i am pregnant?

Thanks
Priyanka

Dr Aniruddha Malpani, MD said...

A HCG level of less than 10 mIU/ml is negative.

However, you should not have done the test so early ! The HCG test should be done 10 days after a blastocyst transfer.

Read more at www.drmalpani.com/hcg.htm

Priyanka Sharma said...

Hello dr,

After 2 days that is 4 weeks of pregnancy ( according to my doctor ) my hcg increased from 5.6 to17 . My doctor said its probably a chemical pregnancy or you are not pregnant . What do you suggest since my hcg triple from last hcg but still too low for 14 dpo what are the chances? Pls advice is there still a hope.

Thanks
Priyanka

Dr Aniruddha Malpani, MD said...

Dear Priyanka,

I don't want to give you false hope

Did you take a HCG injection recently ?

Priyanka Sharma said...

Hello doctor,

No I am not taking any hcg injection but I am estrogen and progesterone medicines

Thanks
Priyanka

Anonymous said...

Hello Doctor, I had 2 4 cell embryo's transfered last Wednesday (17th) It was a 2 day transfer so my question is when is the earliest I can test or when will the symtpoms start
Cheers

Dr Aniruddha Malpani, MD said...

Symptoms are too unreliable, sorry

Do a blood test for HCG 14 days after the transfer

Read more at www.drmalpani.com/hcg.htm

Best of luck !

Dr Malpani

Anonymous said...

Hi, myself and partner are going through Icsi at the moment. We have had 2 BFN before and now this is our 3rd attempt again with a constructed cycle. But I have a horrible gut feeling its a BFN again,I had cramp for the first few days, and had one tiny bit of blood, but now the cramps away n I have sore breasts. I had cramp all the way through my last 2 and was wondering is this a good or bad sign? I have been so scared this time and crying myself to sleep in fear of it being a negative again please help xx Claire xx

Anonymous said...

Hello Doctor,

Today is my 4th day after a 5 day blastocyst transfer. Today I took the pregnancy test measuring hcg 20miu or more. However, it turned out negative. Does that mean my cycle has failed?

Thank for the response in advance.

Dr Aniruddha Malpani, MD said...

You tested too early - please be patient.

Best of luck !

Dr Malpani

Priyanka Sharma said...

Hello doctor,

My ET was on 13april and it was 5 days blastocyst . But my beta level is only 98 miu today. Although its doubling in 48 hrs . Please let me if there is still any hope .

Regards
Priyanka

Dr Aniruddha Malpani, MD said...

As long as the HCG is doubling, this is a good sign !

Best of luck !

Dr Malpani

Anonymous said...

Hi doctor I have just had my two embryos replaced yesterday and I feel nothind different no pain,no cramps does that mean bad news or simply nothing...am I suppose to feel implntation???

Dr Aniruddha Malpani, MD said...

No, you cannot "feel "
implantation! Embryos are microscopic !

Can you send me more details about your IVF cycle ? What were the meds which were used for
superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood ? What was the endometrial thickness ?
How many embryos were transferred ?
What was the embryo quality ? DO YOU HAVE PHOTOS OF YOUR EMBRYOS ? You can see what embryos should look like at http://www.drmalpani.com/embryos.htm
Can you please send me the printed treatment summary from your IVF clinic ?

Best of luck !

Dr Malpani

Anonymous said...

Sorry I don't have ne of this because my doctor has it... I have add frozen embryo replacment in my natural cycle....I had 25 eggs,11 fertilised of which 1 was transferred and didn't work and know two have bin transferred yesterday....I have been told all my levels r gud.....I had my daughter naturally 6 years ago...normal forecep delivery...the rest of the embryos generated so they disposed them.

Dr Aniruddha Malpani, MD said...

You need to be better informed ! Patients cannot afford to leave everything upto the doctor !

Anonymous said...

I saw my embryos they looked really gud one was almost about to hatch they showed me the cells that were coming out of the embryo......my period date is on the 4 th and testing date the 10 th so wat do I expect on the 4th and am I suppose to feel heavy.

Anonymous said...

Hello doctor,
This is my sixth day post 5days blastocyst transfer. Today I had my blood tes done. The test results say hormone Beta Hcg, serum by CMIA as <1.2. Does that mean I am not pregnant? How to interpret this result? Is there any hope of me being pregnant?

Dr Aniruddha Malpani, MD said...

This is a negative HCG, sorry. However, you could try repeating it again in 3 days

Dr Malpani

Anonymous said...

Hello, doc...

I am 7days post ET, I have had no symptoms whatsoever. Waiting it out till the 2WW is here. I am curious to know if this is normal?

anand said...

Dear Dr, Thanks a lot for your information's regards to IVF treatment,Ver help ful, I am doing My 2 IVF ,we had 16th April 2013 ,3 Day ET, we have not felt any pregnancy symptoms during 2WW period.

we planned to do the blood test on 3rd May 2013, we stop the progestogen , Oil injection and medicine. can we do test on 3rd May 2013.

Kindly suggest what should we do if incase is not IVF positive

Dr Aniruddha Malpani, MD said...

Yes, you can do the HCG on 3 May. Read more at www.drmalpani.com/hcg.htm

Why are you taking progesterone injections ? They are very painful. Vaginal progesterone is much more effective !

Can you send me more details about your IVF cycles ? What were the meds which were used for
superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood ? What was the endometrial thickness ?
How many embryos were transferred ?
What was the embryo quality ? DO YOU HAVE PHOTOS OF YOUR EMBRYOS ? You can see what embryos should look like at http://www.drmalpani.com/embryos.htm
Can you please send me the printed treatment summary from your IVF clinic ?

Anonymous said...

Hi Dr., I had a 5 day blastocyst ET 2 days ago. We went through ICSI because my eggs' shell was too hard for sperms to get through (first regular IVF failed because of that, none of my 11 eggs fertilized). This time, 9 eggs were recovered, 7 fertilized, produced 4 embryos, 3 blastocysts. My question is, if the shell was too hard for sperms to get in and fertilize the eggs, would it be possible for the blastocyst to fail hatching since the shell is/was too hard? We saw our embryo before the ET and it was perfectly round, no signs of hatching just yet.

Thank you in advance for your answer.

Dr Aniruddha Malpani, MD said...

No, total failure of fertilisation is never because the shell ( zona) of the egg is "too hard" ! It's usually because of sperm dysfunction. ICSI resolves this problem effectively.

Anonymous said...

I know that failure of fertilization is most commonly because of sperm dysfunction but that wasn't our case. In our first IVF trial, when they put the sperms with the 11 eggs, 3 days later, they said the sperms were still swimming around my eggs but all my eggs were intact and not fertilized. My husband's sperm tests have always come back normal, normal motility, etc. So anyways, the fact that the zona is too hard for sperms to get in does not mean that it won't let my embryo hatch?

Dr Aniruddha Malpani, MD said...

Just because your sperm were swimming after 3 days does not mean they were functionally competent enough to fertilise your eggs ! The fact that fertilisation occurred after ICSI proves that the sperm are dysfunctional ! Your zona is fine, so please stop worrying about its hardness !

Anonymous said...

I am going threw the same thing right now I have no symptoms at all

Muskan said...

Dear Dr,
Please advise -
I had a day 3 ET with 2 embryos , one 4 cell and one 2 cell.
It has been 10 days since ET.
I have had no symptoms of cramps/morning sickness / spotting / sore breasts etc.
I have had occasional nausea but my Dr said that it could be attributable to the progesterone.
Please help me with the following questions -
Are no symptoms a cause for worry?
What is the earliest I should do a beta hcg test?
Is it ok to do a home pregnancy test now after 10 days of ET or are they still likely to throw wrong results?

Dr Aniruddha Malpani, MD said...

Dear Muskan,

Day 3 embryos should have 8 cells. You can see what embryos should look like at www.drmalpani.com/embryos.htm

If your embryos had only 4 cells and 2 cells, this means they had arrested and the chances of success are very poor, sorry

Can you send me more details about your IVF cycle ? What were the meds which were used for
superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood ? What was the endometrial thickness ?
How many embryos were transferred ?
What was the embryo quality ? DO YOU HAVE PHOTOS OF YOUR EMBRYOS ? You can see what embryos should look like at http://www.drmalpani.com/embryos.htm
Can you please send me the printed treatment summary from your IVF clinic ?

Anonymous said...

Dear dr.

Thank you for all your advise. But I have one question I'm on day two of a fet. I had two 5d eggs transfered. I'm having no symptoms but one a warm belly to the touch, not normal for me. Does that mean it didn't work.? I do have a pic of my eggs and they look good, the embryologist did a assistant hatching on them. I am on 2ml a day progestron shots and twice a week on .06 ml estrodial shots. Thank you for ur help


Stacie

Anonymous said...

Hi doctor,I had my embryo replacment on Saturday and my period date is tomorrow but the doctor told me to do the test on the 10 th........I had some period type cramps and I tested my self on Wednesday and Thursday afternoon my result came positive twice......is that too early to b excited for and I had two embies replaced.

Dr Aniruddha Malpani, MD said...

If your doctor gave you a HCG trigger shot, this could be a false positive test result.

p r shah said...

Hello sir
my wife is normal but i have vas absent
I had done my ivf treatment with tesa

I had done my et on 2nd day with 3 embryo
1 is 4 cell
2 and 3 is 2 cell
So sir i want to know that it is a normal level of embryo on 2nd day?
My wife age is 24 yrs how many chansses to get result in positive

p r shah said...

Hello sir
my wife is normal but i have vas absent
I had done my ivf treatment with tesa

I had done my et on 2nd day with 3 embryo
1 is 4 cell
2 and 3 is 2 cell
So sir i want to know that it is a normal level of embryo on 2nd day?
My wife age is 24 yrs how many chansses to get result in positive

Anonymous said...

Hello doctor,
I had a 5day blastocyst transferred on 22nd april2013. However, the cycle has failed. Today my periods started. My question is can I go for the frozen embryo transfer cycle immediately after this failed cycle. Is the success rate good if I go for back to back cycle. I still have 5 blastocysts frozen. Please guide me. I am confused.

Anonymous said...

Had a single 2 day 4 cell top grade embryo transfered on 4th May 2013. I have to give myself a quarter dose of Ovitrell 250 injection on the 7th May. How long will it stay in my system maybe causing a false positive home pregnancy test

Dr Aniruddha Malpani, MD said...

Yes, you can do a back to back cycle if your Day 3 scan shows you are downregulated

Can you send me more details about your IVF cycle ? What were the meds which were used for
superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood ? What was the endometrial thickness ?

What was the embryo quality ? DO YOU HAVE PHOTOS OF YOUR EMBRYOS ? You can see what embryos should look like at http://www.drmalpani.com/embryos.htm
Can you please send me the printed treatment summary from your IVF clinic ?

Anonymous said...

Hi Dr Malpani!
Any thoughts on empirical use of prednisolone or other steroids preimplantation to prevent the immune system from attacking the embryos? I have tubal factor IF and had failed IVF a year ago with nearly empty follicles that resulted in poor quality embryos. Im on a different drug this time around, with better response. A larger number of ova were retrieved. I want to give this second cycle my best shot. Will empirical steroids and aspirin help? When are they introduced for how long and at what dose? Testing for NK cell or antibodies is not available in my clinic
Thanks, Leona.

Dr Aniruddha Malpani, MD said...

Dear Leona,

I do not believe the immune system can "attack " the embryos - the uterus is an "immunologically privileged" site and can accept all embryos !

No one is sure whether empirical steroids help - but this is a low cost low risk intervention, so you can try it out if it will give you peace of mind.

NK cell testing is a waste of time and money. You can read about this at www.drmalpani.com/wasteful-infertility-tests.htm

Please send me photos of your embryos

Anonymous said...

Dear doctor ,
I had 3 embryos transferred of 8cell 7cell and 5 cell on may 1st '13. My estradiol value was around 1700 at the time of egg collection and ER was 10mm. But my ANA value was slightly higher 41. Is this harmful to the embryo ?

p r shah said...

thanks 4 reply answer sir,
I had done my laparoscopy aboout 1 year ago and doctor said that all are normal .
Uterus wall thickness are also normal but i dont know in unit.
My e2 level is start with 25 - 282 - 800 - 900 - 2600 -7000 - 11000 and stop the injection on 12 th day after it my e2 level are 4000 on 14 th day.
in the er 9 follicles are pick up
2 follicle are the bad quallity
7 follicles are done icsi
And 3 follicles are fertlized. My et on the 2nd day embryos are in 4 cell -2 cell - 2 cell
So sir plz reply

Dr Aniruddha Malpani, MD said...

No, ANA ( antinuclear antibodies) do not harm your embryos ! Your embryos are safe in your uterus

Dr Malpani

Anonymous said...

Dear Dr, had my beta test today 10 days post ET ( 2 5day compacted grade 4 blasts) and it came back at 18.4miu/ml. I am worried this might be very low.. What is your opinion?

Thank u

Dr Aniruddha Malpani, MD said...

This is a very low HCG. It maybe a result of the HCG trigger shot given prior to egg collection.

I have never heard of a compacted blastocyst !

Can you send me more details about your IVF cycle ? What were the meds which were used for
superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood ? What was the endometrial thickness ?
DO YOU HAVE PHOTOS OF YOUR EMBRYOS ? You can see what embryos should look like at http://www.drmalpani.com/embryos.htm
Can you please send me the printed treatment summary from your IVF clinic ?

Anonymous said...

Dear doctor I had my et on the 26th and due to test on Monday I have had no bleeding or spotting is this a good sign?

Anonymous said...

Thank u for your prompt reply to my question. Where can i send u all the info mentioned in your reply? How many days post hcg trigger shot can still be detected in blood!? Had 5000ml of choriomon injected on 22/04 and beta test ob 09/04. Will repeat beta tomorrow 11th! God bless you! Thanks

Dr Aniruddha Malpani, MD said...

HCG can be detected in the urine for about 7-10 days after a 5000 IU injection of HCG

I need more information to be able to provide you with intelligent advice.

Could you please send me your medical details by filling in the form at www.drmalpani.com/malpaniform.htm so that I can guide you better?



Kimberley Rodman said...

Hi doctor

I am 8 days past 3 day 1 8cell ET I have been having mild cramps all the time and on day 4 they were pretty painful I have also had an mild dull headache for 4 days now I am drinking 2l of water a day and different fruit juices.

I am taking 400 mg cyclogest perssaries and I'm on evorel 100 patches and 5mg folic acid and 75 mg aspirin.

Is this a bad sign?

Dr Aniruddha Malpani, MD said...

Dear Kimberly,

Uterine cramping is quite common, so please don't worry about it

Best of luck !

Dr Aniruddha Malpani, MD
Malpani Infertility Clinic, Jamuna Sagar, SBS Road, Colaba
Bombay 400 005. India
Tel: 91-22-22151065, 22151066, 2218 3270, 65527073

Helping you to build your family !

My Facebook page is at www.facebook.com/Dr.Malpani

You can follow me on twitter at https://twitter.com/drmalpani

Watch our infertility cartoon film at http://www.ivfindia.com

Read our book, How to Have a Baby - A Guide for the Infertile Couple,
online at www.DrMalpani.com !

Read my blog about improving the doctor-patient
relationship at http://blog.drmalpani.com

Kimberley Rodman said...

Hi thanks for your quick reply i was just wondering what you think about the headache that i have had for a total of 4 days now?

Dr Aniruddha Malpani, MD said...

Often the medicines used for luteal phase support may cause a headache, so this is no reason to worry ! Get your husband to give you a massage - this will help to relieve them !

Anonymous said...

Hi sir,

I had a FET on 30th April.I have got my first beta today i.e 15 th of may.My value is 116.But my doc gave me HCG 5000 on 14th morning.So is this value because of my HCG injection or is it a good beta.Kindly advise.

Dr Aniruddha Malpani, MD said...

This sounds very suspicious ! There is no point in giving HCG in a FET cycle - especially so many days after the ET !

HCG's action mimics that of LH ( luteinising hormone) and it provides luteal phase support when there is a corpus luteum.

I think your doctor is taking you for a ride. Yes, this level of HCG fits in with the residual effects of an IM injection of 5000 IU HSCG taken 24 hours earlier.

Repeat the test after 2 days, and don't take any more HCG injections. The level will drop.

Read more at www.drmalpani.com/hcg.htm

Anonymous said...

I underwent ivf with icsi. 12 eggs retrived inbetween 9 matured and fertilised and 6 were survived on 5th day. Inbetween only one 3bb grade which is full blastocyst and others were just morula and early blastocyst which couldnot graded. Embryologist did assisted hatching also.
As we dont want twins ,we transfered single 3bb graded blastocyst.
Is our decision right?

Anonymous said...

Hi sir,Thnx for the prompt reply.
Sir mine is case of low AMH.Till date I have gone through two fresh IVF cycle.The second one included the blastocyst transfer also.Both the cycles were failure.My doc suggested me to go for egg donor.So I went for the FET with the egg donor and my two freezed embryo of good quality.My ET is always good.It was 10.5 when I took the transfer.After the Transfer,my doc kept me on progesterone support and HCG 5000 inj twice a week.My beta came 116.I know it can be the result of HCg injc.My doc has advised me to go for another beta hcg test.
sir what do you think about my case.Do u have any advise.I am really shattered.What should I do next.My age is 29.

Dr Aniruddha Malpani, MD said...

You definitely need to find a better doctor !