Wednesday, March 27, 2013

IVF FAQs - If my embryos do not implant , what happens to them ?

The embryo(s) which are transferred to your uterus are just microscopic ball of cells. You cannot see your embryo with your naked eye; you need a microscope , which would enlarge it several hundred times , before you can view it.  When your embryos fail to implant and give rise to a pregnancy, they die and disintegrate. Cells die in the human body all the time, and these dead cells are removed by your body’s scavenging machinery. When you get periods after a failed cycle, only the endometrium which is formed during that particular IVF cycle is sloughed off. Since you took lots of hormones , your endometrial lining might be thicker than usual and you might experience heavier menstrual bleeding or you might have more clots (which appears like a tissue) than you normally do. This doesn’t mean you are having a miscarriage or that the transferred embryo was expelled.

If one of my embryos implant, what happens to the other embryo(s) which was transferred along with it?

The embryos which did not implant die and disintegrate. They are removed by your bodies cleaning machinery. You do not need a menstrual period to remove them from your uterus and neither do they harm your developing baby, so do not panic ! 

This is an excerpt from our forthcoming, book, The Expert Patient's Guide to IVF. This being authored by our expert patient, Manju and me.

 You can email Manju at manjupadmasekar@yahoo.com

Her blog is at www.myselfishgenes.blogspot.com

36 comments:

  1. Anonymous10:12 AM

    Thank you so much for the information. I was searching for an answer but it was so difficult, doesn't seem like anyone interested to know when the embryos go when it was not implanted.

    ReplyDelete
    Replies
    1. The embryo dies and the cells get silently reabsorbed

      Delete
  2. Anonymous2:13 PM

    I am day 6 after frozen embryo transfer. The egg was starting to hatch before is was inserted into my uterus. Last night I woke to go to the toilet (pee)and noticed a small white blot in the bowl which I felt . Could this be my failed embryo?

    ReplyDelete
    Replies
    1. No. Embryos are microscopic and cannot be seen with the naked eye. Please don't let your mind play games with you

      Delete
  3. I had 2 frozen embryos on the 27th October
    On Wednesday 9th November I got my hcg results and were 647. Thursday the day after I had cramps and also a bit of bleeding, the bleeding was more pink than red but then did have a bit of red as day went on. Friday I went for bloods and my hcg dropped to 430. I have to go for bloods on Monday. I'm just wanting to know could I have lost one embryo and the other could still be ok. And maybe Monday the hcg picks up again
    Thank you. I'm so worried

    ReplyDelete
    Replies
    1. I am sorry, a drop in your HCG means you have miscarried

      No, the HCG will not rise now, sorry

      Delete
  4. Anonymous5:44 PM

    I had ET on 3 Feb(5 day transfer) and today is my 8th day (3 embryo transfer)still don't feel any symptoms. When I should go for test becoz my Dr. Called me on 23rd Feb but I think it is so long to wait. How I can know everything is OK. Thanku

    ReplyDelete
    Replies
    1. You can do a beta HCG 12 days after a Day 3 transfer

      Read more at www.drmalpani.com/knowledge-center/articles/hcg

      Delete
  5. I had a day 5 transfer on April19th. Just 1hatching embryo. I took a hpt yesterday and it was negative. Could I still be too early? It was an early detection test. I go for my beta in 2 days. Thoughts?

    ReplyDelete
    Replies
    1. I agree this is not good news, sorry

      Can you send me more details about your IVF cycle ?
      DO YOU HAVE PHOTOS OF YOUR EMBRYO ?

      You can see what embryos should look like at http://www.drmalpani.com/knowledge-center/ivf/embryos

      What were the meds which were used for
      superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood at the time of the HCG trigger ? What was the endometrial thickness ?
      How many embryos were transferred ?
      What was the embryo quality ?
      Can you please send me the printed treatment summary from your IVF clinic ?

      Delete
  6. Follistem 150iu Ovidrel
    13 follicles harvested
    7 ICSI
    E2 2371.50

    FET
    e2 1163.30
    EDO 11
    1 embryo
    Grade 4aa

    ReplyDelete
    Replies
    1. I need photos of your embryo please. All good clinics provide these routinely and proactively

      Delete
  7. I can't get it over the weekend. based on this info, what are your educated thoughts? Also, I am 32years old with 1 healthy 3 year old little girl. If that info helps. My husband was diagnosed with a morphology issue.

    ReplyDelete
  8. Melisss1:49 AM

    What does it mean if you transferred 2 embryos got a negative pregnancy beta. However, 3 weeks later your HCG is 1100 . Nothing is seen om ultrasound to get a conclusive image for ectopic. Is the embryo just absorbed into the body that is producing the numbers to keep rising.
    Thank you,
    Melisss

    ReplyDelete
    Replies
    1. You seem to have an ectopic pregnancy

      Read more at http://www.drmalpani.com/knowledge-center/articles/ectopic

      The ultrasound scan is not meant to visualise the ectopic pregnancy. If you want that long, there is a risk it may rupture !

      Delete
  9. I had my transfer on 6/22/2017 and tested HPT on 6/24/2017. I am 43 years old had 12 eggs 11 fertilized and made it to blastocyst. I had them all tested for PGD. My results 2 days post was negative. should I be worried.

    ReplyDelete
    Replies
    1. You tested too early !
      Read more at www.drmalpani.com/knowledge-center/articles/hcg

      Can you send me more details about your IVF cycle?
      DO YOU HAVE PHOTOS OF YOUR EMBRYOS ?

      You can see what embryos should look like at http://www.drmalpani.com/knowledge-center/ivf/embryos

      What were the meds which were used for
      superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood at the time of the HCG trigger ? What was the endometrial thickness ?
      How many embryos were transferred ?
      What was the embryo quality ?
      Can you please send me the printed treatment summary from your IVF clinic ?

      Delete
  10. Anonymous10:12 AM

    Hi I had my transfer on 6/9 2 embryo and they used embryo glue but after transfer I have cramping like periods cramps what that means ? Didn't work ?

    ReplyDelete
  11. Anonymous10:21 AM

    I had two blastocyst transfer on 6 sept.First beta hcg test was on 18 sept.HCG level was 715.2.On 25 sept I started bleeding which last for same day only.On 27sept, i did a urine test at home and it shows positive.What does it mean?I am on progynova,progestetone gel,ecosprin.Tranostat was adviced when i started bleeding.

    ReplyDelete
    Replies

    1. You need to do a vaginal ultrasound scan to confirm the pregnancy is healthy

      Read more at http://www.drmalpani.com/knowledge-center/articles/atlas-of-ultrasound-images-during-early-pregnancy

      Delete
  12. 19 day scene transfer, positive test, hcg, on day 14 way 158. We did two embryos on day three. I have had random spoting. Could this be from the embryo that didn't make it.

    ReplyDelete
    Replies
    1. Congrats !

      Spotting and bleeding during pregnancy is quite common. This usually comes from the uterus and does not harm the baby

      Please rest and drink lots of fluids and it should stop.

      Delete
  13. Anonymous11:17 AM

    I got my ET done with donor eggs on 28th sept...got my hcg done on 12th october that showed hcg level as 2207...meanwhile i suffered from severe UTI with blood clots in urine...my urine routine test showed innumerable pus cells and protein traces..took oral antibiotics and still blood clots continued to pass with urine...got admitted in hospital from 14-17 oct for injectable antibiotics...my repeat hcg test showed hcg level of 12181 and urine culture showed organism growth...doctor has suggested sonography after 8 days, around 24 or 25 oct...my concern is am still getting blood clots with or without urine. What does that mean? I am also suffering from headache, nausea without vomitting, fatigue.
    Please suggest.

    ReplyDelete
    Replies
    1. The HCG is rising well, and this is reassuring

      You need to do a vaginal ultrasound scan to confirm the pregnancy is healthy

      Read more at http://www.drmalpani.com/knowledge-center/articles/atlas-of-ultrasound-images-during-early-pregnancy

      We look forward to helping you to have a baby !

      Delete
  14. I had 3 embryos transferred . I got positive result at 18dp3t. But my hcg level was 200 scince then I'm taking hcg shot every 5 th day and will test again after 12 days . What do u think? Is 200 too low ???

    ReplyDelete
  15. Hi,
    I got positive result after after 18 day after 3 days transfer(3 embryos )
    Hcg level was 200
    My doc put me on hcg shots for 12 days.without monitoring my hcg level more . My next test will be after 5 days.
    Why she is doing this. Is 200 low?
    Thanks

    ReplyDelete
    Replies
    1. This is poor medical treatment

      Read more at www.drmalpani.com/knowledge-center/articles/hcg

      Repeat the HCG test in 2 days. In a healthy pregnancy, it should double

      We look forward to helping you to have a baby !

      Dr Aniruddha Malpani, MD
      Malpani Infertility Clinic, Jamuna Sagar, SBS Road, Colaba
      Bombay 400 005. India
      Tel: 91-22-22151065, 22151066, 2218 3270, 65527073

      Helping you to build your family !

      PS Watch our infertility cartoon film at http://www.ivfindia.com

      Read our book, How to Have a Baby – A Guide for the Infertile Couple,
      Online at www.DrMalpani.com !

      Read my blog about improving the doctor-patient
      Relationship at http://doctorandpatient.blogspot.com/

      Delete
  16. Anonymous11:10 PM

    Can implantation happen on third day after fertilization
    Assuming fertilization today (5nov) and implantation on 7 Nov
    If it happens then is it ectopic pregnancy?

    ReplyDelete
    Replies
    1. Implantation is a silent process and we cannot determine when it happens

      Can you send me more details about your IVF cycle ?
      DO YOU HAVE PHOTOS OF YOUR EMBRYOS ?

      You can see what embryos should look like at http://www.drmalpani.com/knowledge-center/ivf/embryos

      What were the meds which were used for
      superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood at the time of the HCG trigger ? What was the endometrial thickness ?
      How many embryos were transferred ?
      What was the embryo quality ?
      Can you please send me the printed treatment summary from your IVF clinic ?

      Delete
  17. On October 31st I had two embryos transferred yesterday was day 8 and I started bleeding is it possible that one embryo have taken and the other one didn't or is it a possibility that both embryos didn't take and I started my cycle

    ReplyDelete
    Replies
    1. Bleeding so soon after an embryo transfer is a bad sign, and suggests your cycle has failed, sorry

      Can you send me more details about your IVF cycles ?
      DO YOU HAVE PHOTOS OF YOUR EMBRYOS ?

      You can see what embryos should look like at http://www.drmalpani.com/knowledge-center/ivf/embryos

      What were the meds which were used for
      superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood at the time of the HCG trigger ? What was the endometrial thickness ?

      What was the embryo quality ?
      Can you please send me the printed treatment summary from your IVF clinic ?

      Delete
  18. Hi. I had fet on Nov 7 wit two embryos. On Nov 20 my beta was negative. My protocol after transfer was progesterone oil every 3 nights, 2 progesterone pills and 2 estradiol vaginally nightly. In the morning I was taking 1 progesterone pill and 1 estradiol.

    ReplyDelete
    Replies
    1. I need more information to be able to provide you with intelligent advise.

      Can you send me more details about your IVF cycles ?
      DO YOU HAVE PHOTOS OF YOUR EMBRYOS ?

      You can see what embryos should look like at http://www.drmalpani.com/knowledge-center/ivf/embryos

      What were the meds which were used for
      superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood at the time of the HCG trigger ? What was the endometrial thickness ?
      How many embryos were transferred ?
      What was the embryo quality ?
      Can you please send me the printed treatment summary from your IVF clinic ?

      Delete
  19. Anonymous7:51 PM

    I had my ivf on nov 21 transferred with 3 embryos.from yesterday Dec 9 am bleeding only when I urinate.,
    Also my hcg level is low. What does it mean ? Kindly any one can answer?

    ReplyDelete
    Replies
    1. This is not good news and suggest your cycle has failed

      What your HCG level. Read more at www.drmalpani.com/knowledge-center/articles/hcg

      Can you send me more details about your IVF cycle ?
      DO YOU HAVE PHOTOS OF YOUR EMBRYOS ?

      You can see what embryos should look like at http://www.drmalpani.com/knowledge-center/ivf/embryos

      What were the meds which were used for
      superovulation ? What was the dose used ? How many follicles did you grow ? How many eggs were collected ? What was the E2 ( estradiol) level in the blood at the time of the HCG trigger ? What was the endometrial thickness ?
      How many embryos were transferred ?
      What was the embryo quality ?
      Can you please send me the printed treatment summary from your IVF clinic ?

      Delete
  20. Hello, i had embryo transfer 30Nov and 11Dec did hcg level tested 47.3 which my doctor confirmed positive. But i'm still worried because am having period-like cramps sometimes but no bleeding or spoting. Is it a good sign?

    ReplyDelete

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