Friday, January 31, 2020

More proof that PGT for aneuploidy testing reduces IVF pregnancy rates

Outcome of in vitro fertilization cycles with preimplantation genetic testing for aneuploidies: let’s be honest with one another

Richard J. Paulson, M.D., M.S.

The process is, unfortunately, quite inefficient, and 50% of potential implantations are lost, even by clinics that have experience with PGT-A and are good enough to be chosen for the STAR trial. In an intention-to-treat analysis, the pregnancy rate is not increased. The time to pregnancy is not shortened and there is no decrease in miscarriage rates.
If 50% of potential implantations are lost, under what circumstances can we justify the use of PGT-A? We should begin by letting our patients know what the latest research shows. Informed consent should be fully informed.

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